Calcium activation of tissue transglutaminase in radioligand binding and enzyme-linked autoantibody immunoassays in childhood celiac disease Short title: Tissue transglutaminase and calcium

نویسندگان

  • Daniel Agardh
  • Bodil Roth
  • Åke Lernmark
  • Pål Stenberg
چکیده

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Calcium activation of tissue transglutaminase in radioligand binding and enzyme-linked autoantibody immunoassays in childhood celiac disease.

BACKGROUND Conflicting data have been published concerning the effect of calcium on binding of autoantibodies to tissue transglutaminase (tTG) in celiac disease (CD). METHODS IgA-tTG and IgG-tTG were measured with radioligand binding assays (RBA) using human recombinant (hr) (35)S-tTG produced in lysate of rabbit reticulocytes and with guinea pig (gp) tTG ELISA in 51 CD children (median: 5.7 ...

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The Diagnostic Value of Serum IgG-Antigliadin, IgA Anti-endomysial and IgA Anti-tissue Transglutaminase Antibodies for Pediatric Celiac Disease

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Anti-Endomysial and Anti-Tissue Transglutaminase Serological Test Compared with Small Bowel Biopsy in the Diagnosis of Celiac Disease

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Access to the Published Version May Require Journal Subscription. Published with Permission From: Blackwell Synergy

version of a paper published in Clinical and experimental immunology. This paper has been peer-reviewed but does not include the final publisher proof-corrections or journal pagination. "Reduction of tissue transglutaminase autoantibody levels by gluten-free diet is associated with changes in subsets of peripheral blood lymphocytes in children with newly diagnosed coeliac disease" Reduction of ...

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تاریخ انتشار 2006